March Madness Sweet 16: Top Model’s Second-Chance Picks & Bracket Insights

March Madness Sweet 16: The Sweet 16 of the 2025 NCAA Tournament kicks off on Thursday, featuring seven teams from the SEC, including Kentucky and Tennessee. These two historic rivals will clash on Friday at 7:39 p.m. ET, with a coveted spot in the Elite Eight at stake. Notably, the Sweet 16 bracket includes only one double-digit seed: No. 10 Arkansas, which will take on No. 3 Texas Tech on Thursday. Should you consider supporting the Razorbacks in their surprising journey? Additionally, which teams should you favor in crucial matchups like Duke vs. Arizona, Michigan vs. Auburn, and Purdue vs. Houston? Before finalizing your March Madness predictions, check out the insights from SportsLine’s reliable computer model regarding the 2025 NCAA Tournament bracket.

SportsLine’s advanced projection model has simulated every tournament game 10,000 times and has consistently excelled in its March Madness predictions, outperforming over 91% of CBS Sports brackets in four of the last six tournaments. It accurately identified 13 of the 16 teams in the Sweet 16, and all four of its predicted Final Four teams remain in contention. The model is also adept at identifying potential upsets, having successfully predicted 25 first-round surprises by double-digit seeds since its launch in 2016.

Why leave your March Madness picks to chance when you can leverage proven technology to enhance your strategy? With the full 2025 NCAA bracket now available, the model has simulated the upcoming matchups, and the results are ready for you to explore exclusively at SportsLine.

Top picks for the 2025 March Madness Sweet 16

No. 2 seed is one of the model’s Sweet 16 picks. Tennessee defeats the Wildcats on Friday, even though they had already lost twice this season cky. The Volunteers have a wealth of playmakers who can take over a game, and Tennessee has experience on their side after making it to the Elite Eight in 2024.

Senior point guard Zakai Zeigler is sixth in the country with an average of 7.4 assists per game, making him one of the top floor generals in college basketball. He scores 13.7 points per game and makes 41.3% of his field goals. With 15 points, six assists, three rebounds, and three steals, Zeigler dominated the stat sheet in Tennessee’s victory over UCLA in the second round. Against a Kentucky defense that is allowing 77.2 points per game this season—which is 308th in college basketball—Zeigler and the Vols should have success.

How to forecast the NCAA bracket for 2025

Additionally, according to SportsLine’s model, the Final Four will include something that hasn’t occurred in nearly two decades. Before committed to any 2025 NCAA bracket choices, you should check out the teams the model is selecting this year because of its history of predicting upsets that blow the brackets.

 

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